?? ???? ????? ???? ????? ?? ?????? ??????? ?????? ?????? ??? ???? ????? ?? ??? ???????? ??? ?? ??? ????? ???? ????? ?? ???? ?? ??? ???? ??????? ?? ?????? ????? ???? ?????? ????? ??????.Advise both clients and caregivers in regards to the hazards of respiratory depression and sedation when OPANA ER is employed with benzodiazepines or other CNS depre